Differential effect of the alkaloid lycorine on rho +, mit +, rho -, and rho° strains of Saccharomyces cerevisiae
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چکیده
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new angle of view on the role of rho/rho kinase pathway in human diseases.
rho-kinase is an effector molecule of rhoa, a monomeric gtp-binding protein, and causes ca2+ sensitization through inactivation of myosin phosphatase. the major physiological functions of rho/rho-kinase cascade include contraction, proliferation and migration in cells.there are some excellent reviews about rho/rho-kinase signal pathway, most of which focus on the specific proteins of the pathwa...
متن کامل($phi,rho$)-Representation of $Gamma$-So-Rings
A $Gamma$-so-ring is a structure possessing a natural partial ordering, an infinitary partial addition and a ternary multiplication, subject to a set of axioms. The partial functions under disjoint-domain sums and functional composition is a $Gamma$-so-ring. In this paper we introduce the notions of subdirect product and $(phi,rho)$-product of $Gamma$-so-rings and study $(phi,rho)$-represen...
متن کاملthe effect of explicit teaching of metacognitive vocabulary learning strategies on recall and retention of idioms
چکیده ندارد.
15 صفحه اولI-28: Role of Mevalonate-Ras Homology (Rho)/Rho-Associated Coiled-Coil-Forming Protein Ki nase-Mediated Signaling Pathway in The Pathogenesis of Endometriosis-Associated Fibrosis
Background: Endometriosis, a disease affecting 3-10% of women of reproductive age, is characterized by the ectopic growth of endometrial glands and stroma surrounded by dense fibrous tissue. Whereas, normal eutopic endometrium shows scarless tissue repair during menstrual cycles, which suggests that the endometriotic tissues have distinct mechanisms of fibrogenesis. During the development of en...
متن کاملWallerian degeneration involves Rho/Rho-kinase signaling.
Local axon degeneration is a common pathological feature of many neurodegenerative diseases, whereas the underlying molecular mechanisms are largely unknown. In this study, we used the degeneration of transected axons, termed "Wallerian degeneration," as a model to examine the possible involvement of Rho. Nogo-66, a myelin-derived inhibitor of axon regeneration, significantly accelerated axon d...
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ژورنال
عنوان ژورنال: Current Genetics
سال: 1985
ISSN: 0172-8083,1432-0983
DOI: 10.1007/bf00436969